DACH1 antibody (AA 300-550)

Catalog No. ABIN5027130

Product Details anti-DACH1 Antibody

Target: DACH1 (Dachshund 1 (DACH1))

Binding Specificity: AA 300-550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACH1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant Dach1 protein (amino acids 300-550) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for DACH1

Target: DACH1 (Dachshund 1 (DACH1))

Alternative Name: Dach1 (DACH1 Products)

Synonyms: DACH antibody, AI182278 antibody, Dac antibody, Dach antibody, E130112M23Rik antibody, dach antibody, dachshund family transcription factor 1 antibody, dachshund 1 (Drosophila) antibody, dachshund family transcription factor 1 S homeolog antibody, dachshund homolog 1 antibody, DACH1 antibody, Dach1 antibody, dach1.S antibody, dach1 antibody, LOC100550020 antibody

Background: DACH1, originally discovered in drosophila eye development, is an essential member of RDGN (Retinal Determination Gene Network). This protein behaves as a tumor suppressor, and its expression is reduced in several cancers. The ectopic expression of DACH1 inhibits cellular proliferation in vitro and tumor growth in vivo. DACH1 is richly expressed in embryonal kidney cells and adult kidney tissues, but dramatically decreases in renal cancer cells.

Molecular Weight: 78 kDa

Gene ID: 1602

UniProt: Q9UI36

Pathways: Feeding Behaviour