PACS1 antibody (AA 150-400)

Catalog No. ABIN5027422

Product Details anti-PACS1 Antibody

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Binding Specificity: AA 150-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant PACS-1 protein (amino acids 150-400) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 1-3 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Alternative Name: PACS-1 (PACS1 Products)

Synonyms: MRD17 antibody, AI325977 antibody, Pacs-1 antibody, phosphofurin acidic cluster sorting protein 1 antibody, PACS1 antibody, Pacs1 antibody

Background: PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.

Molecular Weight: 106 kDa

Gene ID: 55690

UniProt: Q6VY07