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ATG4A antibody (AA 102-113) (Biotin)

ATG4A Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal Biotin
Catalog No. ABIN5065986
  • Target See all ATG4A Antibodies
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    Binding Specificity
    • 15
    • 11
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-113
    Reactivity
    • 68
    • 29
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 64
    • 4
    Polyclonal
    Conjugate
    • 31
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4A antibody is conjugated to Biotin
    Application
    • 45
    • 26
    • 24
    • 20
    • 14
    • 13
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.,Detects ~45 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the mid-protein of Human ATG4A (aa. 102-113)
    Isotype
    IgG
    Top Product
    Discover our top product ATG4A Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:1000 dilution of ABIN5065986 was sufficient for detection of ATG4A in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
    Alternative Name
    ATG4A (ATG4A Products)
    Synonyms
    apg4a antibody, autl2 antibody, F6E13.27 antibody, APG4A antibody, zgc:111958 antibody, Aut2a antibody, AUTL2 antibody, AI627006 antibody, AV169859 antibody, Apg4a antibody, Atg4al antibody, Autl2 antibody, Atg4a antibody, autophagy related 4A cysteine peptidase L homeolog antibody, autophagy related 4A cysteine peptidase antibody, Peptidase family C54 protein antibody, ATG4 autophagy related 4 homolog A (S. cerevisiae) antibody, autophagy related 4A, cysteine peptidase antibody, atg4a.L antibody, ATG4A antibody, AT2G44140 antibody, atg4a antibody, Atg4a antibody
    Background
    Autophagy related 4A, cysteine peptidase (ATG4A or APG4A) is a C-54 cysteine protease that also belongs to the family of autophagin proteins, and is primarily found in skeletal muscle and brain. ATG4A is involved in cellular autophagy and has been studied as a target for cancer therapy. Specifically it cleaves GATE-16. Mutations in the ATG4a gene is critical for redox regulation and inhibits autophagosome formation.
    Gene ID
    115201
    NCBI Accession
    NP_001308216
    UniProt
    Q8WYN0
    Pathways
    Autophagy
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