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AKR1C2 antibody (AA 224-323)

AKR1C2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3C11 unconjugated
Catalog No. ABIN514927
  • Target See all AKR1C2 Antibodies
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Binding Specificity
    • 10
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-323
    Reactivity
    • 47
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 6
    Mouse
    Clonality
    • 44
    • 3
    Monoclonal
    Conjugate
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C2 antibody is un-conjugated
    Application
    • 37
    • 25
    • 17
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant AKR1C2.
    Sequence
    EEPWVDPNSP VLLEDPVLCA LAKKHKRTPA LIALRYQLQR GVVVLAKSYN EQRIRQNVQV FEFQLTSEEM KAIDGLNRNV RYLTLDIFAG PPNYPVSDEY
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    AKR1C2 (AAH63574, 224 a.a. ~ 323 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3C11
    Isotype
    IgG2a
    Top Product
    Discover our top product AKR1C2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hevir, Vouk, Sinkovec, Ribi?-Pucelj, Rižner: "Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 217-26, (2011) (PubMed).

    Takahashi, Bains, Pfeifer, Grigliatti, Reid, Riggs: "Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 36, Issue 6, pp. 991-4, (2008) (PubMed).

  • Target
    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
    Alternative Name
    AKR1C2 (AKR1C2 Products)
    Synonyms
    AKR1C-pseudo antibody, BABP antibody, DD antibody, DD2 antibody, DDH2 antibody, HAKRD antibody, HBAB antibody, MCDR2 antibody, SRXY8 antibody, Akr1c21 antibody, aldo-keto reductase family 1 member C2 antibody, aldo-keto reductase family 1, member C2 antibody, AKR1C2 antibody, Akr1c2 antibody
    Background
    Full Gene Name: aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)
    Synonyms: AKR1C-pseudo,BABP,DD,DD2,DDH2,HAKRD,HBAB,MCDR2
    Gene ID
    1646
    Pathways
    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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