PARP1 antibody (Cleavage Site)

Catalog No. ABIN531998

Product Details anti-PARP1 Antibody

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Binding Specificity: Cleavage Site

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of PARP1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide corresponding to amino acids near 214/215-cleavage site of human PARP1.

Clone: 194C1439

Isotype: IgG

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.05 % BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PARP1 antibody (ABIN531998)

Meng, Henson, Patel: "Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells." in: American journal of physiology. Cell physiology, Vol. 293, Issue 2, pp. C749-60, (2007) (PubMed).

Lee, Kang, Seo, Choi, Park, Park: "Expression of tumor endothelial marker 7 mRNA and protein in the dorsal root ganglion neurons of the rat." in: Neuroscience letters, Vol. 402, Issue 1-2, pp. 71-5, (2006) (PubMed).

Lee, Bae, Park, Seo, Lee, Suh, Park: "Cloning, characterization and neuronal expression profiles of tumor endothelial marker 7 in the rat brain." in: Brain research. Molecular brain research, Vol. 136, Issue 1-2, pp. 189-98, (2005) (PubMed).

Ko, Shen, Chen: "Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species." in: Free radical biology & medicine, Vol. 36, Issue 7, pp. 897-910, (2004) (PubMed).

Nanda, Buckhaults, Seaman, Agrawal, Boutin, Shankara, Nacht, Teicher, Stampfl, Singh, Vogelstein, Kinzler, St Croix: "Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R." in: Cancer research, Vol. 64, Issue 23, pp. 8507-11, (2004) (PubMed).

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: PARP1 (PARP1 Products)

Synonyms: ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody

Gene ID: 142

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location