SHC1 antibody (SHC (Src Homology 2 Domain Containing) Transforming Protein 1)

Details for Product anti-SHC1 Antibody No. ABIN532687
Antigen
Reactivity
Human
305
238
185
12
11
8
7
6
3
3
3
3
2
1
1
1
1
Host
Mouse
279
44
Clonality (Clone)
Monoclonal ()
Conjugate
This SHC1 antibody is un-conjugated
14
10
10
10
10
10
10
9
8
5
5
5
5
5
2
2
2
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
226
104
93
66
59
56
18
13
11
9
5
4
3
1
Options
Purpose Mouse monoclonal antibody raised against partial recombinant SHC1.
Immunogen Recombinant His/ABD fusion protein corresponding to amino acids 484-583 of human SHC1.
Clone 47F4
Isotype IgG1, kappa
Purification Purified
Antigen
Alternative Name SHC1 / SHC (SHC1 Antibody Abstract)
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
Application Notes Western Blot (1:5000)
Immunoprecipitation (1 µL)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Buffer In HEPES, 150 mM NaCl (50 % glycerol, 0.01 % BSA, 0.03 % sodium azide)
Storage -20 °C
Storage Comment Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Supplier Images
Image no. 1 for anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1) antibody (ABIN532687) Immunoblot analysis of cell lysates. Lane 1 : A-431 cell lysate. Lane 2 : HeLa cell l...
Product cited in: Zhang, Lorenz, Ravichandran: "Role of Shc in T-cell development and function." in: Immunological reviews, Vol. 191, pp. 183-95, 2003 (PubMed).

Ravichandran: "Signaling via Shc family adapter proteins." in: Oncogene, Vol. 20, Issue 44, pp. 6322-30, 2001 (PubMed).