Clusterin antibody (AA 1-333)

Catalog No. ABIN532958

Product Details anti-Clusterin Antibody

Target: Clusterin (CLU)

Binding Specificity: AA 1-333

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Clusterin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against partial recombinant CLU.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to amino acids 1-333 of human CLU.

Clone: 1A11

Isotype: IgG1

Application Details

Application Notes: Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (10 % glycerol, 0.02 % sodium azide).

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Clusterin antibody (ABIN532958)

Saratsis, Kambhampati, Snyder, Yadavilli, Devaney, Harmon, Hall, Raabe, An, Weingart, Rood, Magge, MacDonald, Packer, Nazarian: "Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes." in: Acta neuropathologica, Vol. 127, Issue 6, pp. 881-95, (2014) (PubMed).

Loison, Debure, Nizard, le Goff, Michel, le Dréan: "Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes." in: The Biochemical journal, Vol. 395, Issue 1, pp. 223-31, (2006) (PubMed).

Redondo, Villar, Torres-Muñoz, Tellez, Morell, Petito: "Overexpression of clusterin in human breast carcinoma." in: The American journal of pathology, Vol. 157, Issue 2, pp. 393-9, (2000) (PubMed).

Target Details for Clusterin

Target: Clusterin (CLU)

Alternative Name: Apolipoprotein J (Apo J) (CLU Products)

Synonyms: LOC100136120 antibody, clu antibody, MGC53055 antibody, zgc:73352 antibody, xclu antibody, MGC89163 antibody, CLU antibody, APO-J antibody, APOJ antibody, CLI antibody, CLU1 antibody, CLU2 antibody, KUB1 antibody, NA1/NA2 antibody, SGP-2 antibody, SGP2 antibody, SP-40 antibody, TRPM-2 antibody, TRPM2 antibody, DAG antibody, RATTRPM2B antibody, SP40 antibody, TRPM2B antibody, Trpm2 antibody, Trpmb antibody, AI893575 antibody, ApoJ antibody, Cli antibody, D14Ucla3 antibody, Sgp-2 antibody, Sgp2 antibody, Sugp-2 antibody, GP80 antibody, gpIII antibody, 40 antibody, clusterin-1 antibody, clusterin L homeolog antibody, clusterin antibody, Clusterin antibody, LOC100136120 antibody, clu.L antibody, clu antibody, CLU antibody, clus antibody, Clu antibody, LOC101113728 antibody

Gene ID: 1191

NCBI Accession: NM_203339

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling