c-MET antibody

Catalog No. ABIN533002

Product Details anti-c-MET Antibody

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-MET antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against partial recombinant MET.

Cross-Reactivity: Human, Mouse

Immunogen: Recombinant protein corresponding to catalytic region of human MET.

Clone: 4AT44

Isotype: IgG1

Application Details

Application Notes: Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-c-MET antibody (ABIN533002)

Sugiura, Kawaguchi, Soejima, Katsumata, Gono, Baba, Kawamoto, Murakawa, Yamanaka, Hara: "Increased HGF and c-Met in muscle tissues of polymyositis and dermatomyositis patients: beneficial roles of HGF in muscle regeneration." in: Clinical immunology (Orlando, Fla.), Vol. 136, Issue 3, pp. 387-99, (2010) (PubMed).

Thanseem, Nakamura, Miyachi, Toyota, Yamada, Tsujii, Tsuchiya, Anitha, Iwayama, Yamada, Hattori, Matsuzaki, Matsumoto, Iwata, Suzuki, Suda, Kawai, Sugihara, Takebayashi, Takei, Ichikawa, Sugiyama et al.: "Further evidence for the role of MET in autism susceptibility. ..." in: Neuroscience research, Vol. 68, Issue 2, pp. 137-41, (2010) (PubMed).

Tyner, Fletcher, Wang, Yang, Rutenberg-Schoenberg, Beadling, Mori, Heinrich, Deininger, Druker, Loriaux: "MET receptor sequence variants R970C and T992I lack transforming capacity." in: Cancer research, Vol. 70, Issue 15, pp. 6233-7, (2010) (PubMed).

Target Details for c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Alternative Name: HGF receptor (MET Products)

Synonyms: AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody

Gene ID: 4233

Pathways: RTK Signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor