ERK2 antibody (pThr202, pThr204)

Catalog No. ABIN533402

Product Details anti-ERK2 Antibody

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Binding Specificity: pThr202, pThr204

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ERK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purpose: Rabbit monoclonal antibody raised against synthetic phosphopeptide of MAPK1/MAPK3.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding T202/T204 of human MAPK1/MAPK3.

Clone: G15-B

Isotype: IgG

Application Details

Application Notes: ELISA (1:20000-1:100000)
Immunofluorescence
Immunoprecipitation
Western Blot (1:5000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM Tris-HCl, pH 8.0 (10 mg/mL BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ERK2 antibody (ABIN533402)

Lee, Shen, Shih, Chou, Tseng, Chin, Liu, Chen, Jiang: "Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts." in: Journal of translational medicine, Vol. 13, pp. 191, (2015) (PubMed).

Tai, Lee, Chen, Wang, Jiang, Su, Shen, Lin, Yeh, Chen, Yeh, Chang: "High nuclear expression of phosphorylated extracellular signal-regulated kinase in tumor cells in colorectal glands is associated with poor outcome in colorectal cancer." in: Annals of diagnostic pathology, Vol. 17, Issue 2, pp. 165-71, (2013) (PubMed).

Tai, Chang, Jiang, Yeh, Su, Wu, Chen, Yeh, Lin, Chen: "Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer." in: Polish journal of pathology : official journal of the Polish Society of Pathologists, Vol. 63, Issue 2, pp. 93-100, (2012) (PubMed).

Target Details for ERK2

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Alternative Name: ERK2 (MAPK1 Products)

Synonyms: ERK-1 antibody, ERK1 antibody, ERT2 antibody, HS44KDAP antibody, HUMKER1A antibody, P44ERK1 antibody, P44MAPK antibody, PRKM3 antibody, p44-ERK1 antibody, p44-MAPK antibody, Erk-1 antibody, Erk1 antibody, Ert2 antibody, Esrk1 antibody, Mnk1 antibody, Mtap2k antibody, Prkm3 antibody, p44 antibody, p44erk1 antibody, p44mapk antibody, ERK antibody, ERK2 antibody, ERT1 antibody, MAPK2 antibody, P42MAPK antibody, PRKM1 antibody, PRKM2 antibody, p38 antibody, p40 antibody, p41 antibody, p41mapk antibody, 9030612K14Rik antibody, AA407128 antibody, AU018647 antibody, C78273 antibody, Erk2 antibody, Prkm1 antibody, p42mapk antibody, zERK2 antibody, MAPK1 antibody, Xp42 antibody, erk antibody, erk2 antibody, ert1 antibody, mapk antibody, mapk1b antibody, mapk2 antibody, mpk1 antibody, prkm1 antibody, prkm2 antibody, mapk1 antibody, mapk1a antibody, xp42 antibody, ATMPK1 antibody, F14N23.9 antibody, F14N23_9 antibody, MITOGEN-ACTIVATED PROTEIN KINASE antibody, mitogen-activated protein kinase 1 antibody, MNK1 antibody, ATMPK2 antibody, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 antibody, T30E16.13 antibody, T30E16_13 antibody, mitogen-activated protein kinase homolog 2 antibody, mitogen-activated protein kinase 3 antibody, mitogen-activated protein kinase 1 antibody, mitogen activated protein kinase 1 antibody, mitogen-activated protein kinase 1 L homeolog antibody, mitogen-activated protein kinase 1 S homeolog antibody, mitogen activated protein kinase 3 antibody, mitogen-activated protein kinase homolog 2 antibody, MAPK3 antibody, Mapk3 antibody, MAPK1 antibody, Mapk1 antibody, mapk1 antibody, mapk1.L antibody, mapk1.S antibody, PfMAP1 antibody, MPK1 antibody, PVX_084965 antibody, LOC9328617 antibody, Tsp_01601 antibody, MPK2 antibody

Gene ID: 5594, 5595

Pathways: MAPK Signaling, RTK Signaling, Apoptosis, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins