FFAR1 antibody

Catalog No. ABIN533478

Product Details anti-FFAR1 Antibody

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FFAR1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of Ffar1.

Cross-Reactivity: Mouse

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to mouse Ffar1.

Clone: G16

Isotype: IgG2a

Application Details

Application Notes: Immunocytochemistry (1 μg/mL)
Flow Cyt (0.5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.1 % proclin, 2.0 % Block Ace).

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at below -20°C. Once thawed, store at 4°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-FFAR1 antibody (ABIN533478)

Hirasawa, Itsubo, Sadakane, Hara, Shinagawa, Koga, Nose, Koshimizu, Tsujimoto: "Production and characterization of a monoclonal antibody against GPR40 (FFAR1; free fatty acid receptor 1)." in: Biochemical and biophysical research communications, Vol. 365, Issue 1, pp. 22-8, (2007) (PubMed).

Steneberg, Rubins, Bartoov-Shifman, Walker, Edlund: "The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse." in: Cell metabolism, Vol. 1, Issue 4, pp. 245-58, (2005) (PubMed).

Hardy, St-Onge, Joly, Langelier, Prentki: "Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13285-91, (2005) (PubMed).

Briscoe, Tadayyon, Andrews, Benson, Chambers, Eilert, Ellis, Elshourbagy, Goetz, Minnick, Murdock, Sauls, Shabon, Spinage, Strum, Szekeres, Tan, Way, Ignar, Wilson, Muir: "The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 11303-11, (2003) (PubMed).

Itoh, Kawamata, Harada, Kobayashi, Fujii, Fukusumi, Ogi, Hosoya, Tanaka, Uejima, Tanaka, Maruyama, Satoh, Okubo, Kizawa, Komatsu, Matsumura, Noguchi, Shinohara, Hinuma, Fujisawa, Fujino: "Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40." in: Nature, Vol. 422, Issue 6928, pp. 173-6, (2003) (PubMed).

Target Details for FFAR1

Target: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Alternative Name: FFAR1 / GPR40 (FFAR1 Products)

Synonyms: FFAR1 antibody, GPR40 antibody, FFA1R antibody, GPCR40 antibody, Gpr40 antibody, free fatty acid receptor 1 antibody, FFAR1 antibody, Ffar1 antibody

Gene ID: 233081

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis