CD147 antibody

Catalog No. ABIN533486

Product Details anti-CD147 Antibody

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against native BSG.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against BSG.

Immunogen: Native purified from human cancer cel line.

Clone: 2G2

Isotype: IgG1

Application Details

Application Notes: Flow Cyt (0.5-1 μg/mL)
Immunoprecipitation (5-10 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.1 % proclin, 2.0 % Block Ace)

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD147 antibody (ABIN533486)

Millimaggi, Mari, DAscenzo, Carosa, Jannini, Zucker, Carta, Pavan, Dolo: "Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells." in: Neoplasia (New York, N.Y.), Vol. 9, Issue 4, pp. 349-57, (2007) (PubMed).

Pistol, Matache, Calugaru, Stavaru, Tanaseanu, Ionescu, Dumitrache, Stefanescu: "Roles of CD147 on T lymphocytes activation and MMP-9 secretion in systemic lupus erythematosus." in: Journal of cellular and molecular medicine, Vol. 11, Issue 2, pp. 339-48, (2007) (PubMed).

Tang, Nakada, Rafferty, Laraio, McCabe, Millar, Cunningham, Snyder, Bugelski, Yan: "Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway." in: Molecular cancer research : MCR, Vol. 4, Issue 6, pp. 371-7, (2006) (PubMed).

Egawa, Koshikawa, Tomari, Nabeshima, Isobe, Seiki: "Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells." in: The Journal of biological chemistry, Vol. 281, Issue 49, pp. 37576-85, (2006) (PubMed).

Chen, Lin, Kanekura, Su, Lin, Xie, Wu, Li, Chen, Chang: "A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma." in: Cancer research, Vol. 66, Issue 23, pp. 11323-30, (2006) (PubMed).

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: CD147 (BSG Products)

Synonyms: EMMPRIN antibody, RPE7 antibody, 5F7 antibody, CD147 antibody, M6 antibody, OK antibody, TCSF antibody, AI115436 antibody, AI325119 antibody, HT-7 antibody, 5A11 antibody, CE9 antibody, HT7 antibody, Ox47R antibody, basignin antibody, wu:fb26a05 antibody, wu:fo98e12 antibody, bsg antibody, prso03 antibody, basigin (Ok blood group) antibody, basigin antibody, basigin (Ok blood group) S homeolog antibody, BSG antibody, Bsg antibody, bsg antibody, bsg.S antibody

Gene ID: 682

Pathways: S100 Proteins