CYP3A7 antibody (C-Term)

Catalog No. ABIN533617

Product Details anti-CYP3A7 Antibody

Target: CYP3A7 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP3A7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against synthetic peptide of CYP3A7.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to C-terminus of human CYP3A7.

Clone: F19 P2 H2

Isotype: IgG1

Application Details

Application Notes: Western Blot (1-2 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.08 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CYP3A7 antibody (ABIN533617)

Kumarakulasingham, Rooney, Dundas, Telfer, Melvin, Curran, Murray: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).

Leeder, Gaedigk, Marcucci, Gaedigk, Vyhlidal, Schindel, Pearce: "Variability of CYP3A7 expression in human fetal liver." in: The Journal of pharmacology and experimental therapeutics, Vol. 314, Issue 2, pp. 626-35, (2005) (PubMed).

Ogino, Nagata, Yamazoe: "Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells." in: Drug metabolism and pharmacokinetics, Vol. 17, Issue 1, pp. 42-6, (2004) (PubMed).

Target Details for CYP3A7

Target: CYP3A7 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))

Alternative Name: CYP3A7 (CYP3A7 Products)

Synonyms: CP37 antibody, CYPIIIA7 antibody, P450-HFLA antibody, cytochrome P450, family 3, subfamily A, polypeptide 7 antibody, cytochrome P450 family 3 subfamily A member 7 antibody, CYP3A7 antibody

Gene ID: 1551

Pathways: Steroid Hormone Biosynthesis