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SIAH1/2 antibody (AA 280-331)

SIAH1/2 Reactivity: Human, Rat, Zebrafish (Danio rerio), Drosophila melanogaster, Pig WB, IP Host: Mouse Monoclonal 8G7H12 unconjugated
Catalog No. ABIN534024
  • Target See all SIAH1/2 products
    SIAH1/2 (Seven in Absentia Homolog 1/2 (SIAH1/2))
    Binding Specificity
    • 15
    • 4
    • 1
    • 1
    AA 280-331
    Reactivity
    Human, Rat, Zebrafish (Danio rerio), Drosophila melanogaster, Pig
    Host
    • 20
    Mouse
    Clonality
    • 20
    Monoclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIAH1/2 antibody is un-conjugated
    Application
    • 20
    • 13
    • 13
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Mouse monoclonal antibody raised against synthetic peptide of SIAH1/SIAH2.
    Specificity
    This antibody is specific to human SIAH 1 and 2 and Drosophila SINA in proliferating cells and stem cells. This antibody does not detect Drosophila SINAH or normal, nondividing cells.
    Cross-Reactivity
    Drosophila melanogaster, Human, Pig, Rat, Zebrafish (Danio rerio)
    Immunogen
    A synthetic peptide corresponding to amino acids 280-331 of drosophila SIAH1/SIAH2.
    Clone
    8G7H12
    Isotype
    IgG1
  • Application Notes
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In tissue culture supernatant (0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze.
  • Schmidt, Park, Ahmed, Gundelach, Reed, Cheng, Knudsen, Tang: "Inhibition of RAS-mediated transformation and tumorigenesis by targeting the downstream E3 ubiquitin ligase seven in absentia homologue." in: Cancer research, Vol. 67, Issue 24, pp. 11798-810, (2007) (PubMed).

  • Target
    SIAH1/2 (Seven in Absentia Homolog 1/2 (SIAH1/2))
    Alternative Name
    SIAH1/SIAH2 (SIAH1/2 Products)
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