RAD51C antibody

Catalog No. ABIN534110

Product Details anti-RAD51C Antibody

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAD51C antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Mouse monoclonal antibody raised against recombinant RAD51C.

Specificity: This antibody is specific to Rad51C.

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant His fusion protein corresponding to human RAD51C.

Clone: 2H11-6

Isotype: IgG1

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-RAD51C antibody (ABIN534110)

Shammas, Shmookler Reis, Koley, Batchu, Li, Munshi: "Dysfunctional homologous recombination mediates genomic instability and progression in myeloma." in: Blood, Vol. 113, Issue 10, pp. 2290-7, (2009) (PubMed).

Chan, Koritzinsky, Zhao, Bindra, Glazer, Powell, Belmaaza, Wouters, Bristow: "Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance." in: Cancer research, Vol. 68, Issue 2, pp. 605-14, (2008) (PubMed).

Kuznetsov, Pellegrini, Shuda, Fernandez-Capetillo, Liu, Martin, Burkett, Southon, Pati, Tessarollo, West, Donovan, Nussenzweig, Sharan: "RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females." in: The Journal of cell biology, Vol. 176, Issue 5, pp. 581-92, (2007) (PubMed).

Fan, Kumaravel, Jalali, Marrano, Squire, Bristow: "Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression." in: Cancer research, Vol. 64, Issue 23, pp. 8526-33, (2004) (PubMed).

Maacke, Hundertmark, Miska, Voss, Kalthoff, Stürzbecher: "Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen." in: Journal of cancer research and clinical oncology, Vol. 128, Issue 4, pp. 219-22, (2002) (PubMed).

Target Details for RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: RAD51C (RAD51C Products)

Synonyms: RGD1563765 antibody, CG2412 antibody, Dm CG2412 antibody, Dmel\\CG2412 antibody, zgc:101596 antibody, RAD51C antibody, Rad51c antibody, ATRAD51C antibody, F4L23.21 antibody, RAS associated with diabetes protein 51C antibody, R51H3 antibody, Rad51l2 antibody, BROVCA3 antibody, FANCO antibody, RAD51L2 antibody, RAD51 paralog C antibody, Rad51 recombinase D antibody, Rad51 DNA recombinase 3 antibody, RAD51C protein antibody, RAD51 homolog C antibody, RAS associated with diabetes protein 51C antibody, RAD51C antibody, Rad51c antibody, Rad51D antibody, rad51c antibody

Gene ID: 5889

Pathways: DNA Damage Repair