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PUMA antibody (AA 76-170)

BBC3 Reactivity: Human WB Host: Mouse Monoclonal 10C5G1 unconjugated
Catalog No. ABIN534456
  • Target See all PUMA (BBC3) Antibodies
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Binding Specificity
    • 21
    • 16
    • 13
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 76-170
    Reactivity
    • 108
    • 40
    • 39
    • 16
    Human
    Host
    • 104
    • 7
    • 1
    Mouse
    Clonality
    • 94
    • 18
    Monoclonal
    Conjugate
    • 52
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PUMA antibody is un-conjugated
    Application
    • 93
    • 34
    • 34
    • 22
    • 22
    • 17
    • 16
    • 14
    • 13
    • 9
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Purpose
    Mouse monoclonal antibody raised against recombinant BBC3.
    Cross-Reactivity
    Human, Rat
    Immunogen
    Recombinant protein corresponding to amino acids 76-170 of human BBC3.
    Clone
    10C5G1
    Isotype
    IgG
    Top Product
    Discover our top product BBC3 Primary Antibody
  • Application Notes
    Western Blot (2.5-5 μg/mL)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.02 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Yu, Zhang, Hwang, Kinzler, Vogelstein: "PUMA induces the rapid apoptosis of colorectal cancer cells." in: Molecular cell, Vol. 7, Issue 3, pp. 673-82, (2001) (PubMed).

    Nakano, Vousden: "PUMA, a novel proapoptotic gene, is induced by p53." in: Molecular cell, Vol. 7, Issue 3, pp. 683-94, (2001) (PubMed).

    Han, Flemington, Houghton, Gu, Zambetti, Lutz, Zhu, Chittenden: "Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11318-23, (2001) (PubMed).

  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Alternative Name
    PUMA (BBC3 Products)
    Synonyms
    BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
    Gene ID
    27113
    Pathways
    p53 Signaling, Positive Regulation of Endopeptidase Activity
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