SOS1 antibody

Catalog No. ABIN535287

Product Details anti-SOS1 Antibody

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Mouse monoclonal antibody raised against synthetic peptide of SOS1.

Sequence: THPSMHRDGP PLLENAHSS

Specificity: This antibody reacts with human SOS1, an ubiquitously expressed 150 KDa intracellular protein.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to human SOS1.

Clone: SOS-01

Isotype: IgG1

Application Details

Application Notes: Western Blot (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS, pH 7.4 (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.

References for anti-SOS1 antibody (ABIN535287)

Harris, Parry, Westwick, Ward: "Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes." in: The Journal of biological chemistry, Vol. 283, Issue 5, pp. 2465-9, (2008) (PubMed).

Xing, Hamaguchi: "Effects of SHIP-1 on MMP2 secretion and invasion of SR3Y1 cells." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 34, Issue 4, pp. 285-93, (2007) (PubMed).

Tarasenko, Kole, Chi, Mentink-Kane, Wynn, Bolland: "T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11382-7, (2007) (PubMed).

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1 (SOS1 Products)

Synonyms: GF1 antibody, GGF1 antibody, GINGF antibody, HGF antibody, NS4 antibody, 4430401P03Rik antibody, 9630010N06 antibody, AI449023 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, son of sevenless homolog 1 (Drosophila) antibody, SOS1 antibody, Sos1 antibody

Target Type: Viral Protein

Gene ID: 6654

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling