CD177 antibody (FITC)

Catalog No. ABIN535939

Product Details anti-CD177 Antibody (FITC)

Target: CD177 (CD177 Molecule (CD177))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD177 antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against native CD177.

Specificity: This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 KDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

Cross-Reactivity: Human, Non-Human Primate

Immunogen: Native purified CD177 from human granulocytes.

Clone: MEM-166

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD177 antibody (FITC) (ABIN535939)

Bauer, Abdgawad, Gunnarsson, Segelmark, Tapper, Hellmark: "Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils." in: Journal of leukocyte biology, Vol. 81, Issue 2, pp. 458-64, (2007) (PubMed).

Sachs, Andrei-Selmer, Maniar, Weiss, Paddock, Orlova, Choi, Newman, Preissner, Chavakis, Santoso: "The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31)." in: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23603-12, (2007) (PubMed).

Mnjoyan, Li, Afshar-Kharghan: "Expression of polycythemia rubra vera-1 decreases the dependency of cells on growth factors for proliferation." in: Haematologica, Vol. 90, Issue 3, pp. 405-6, (2005) (PubMed).

Target Details for CD177

Target: CD177 (CD177 Molecule (CD177))

Alternative Name: CD177 (CD177 Products)

Synonyms: HNA-2a antibody, HNA2A antibody, NB1 antibody, NB1 GP antibody, PRV-1 antibody, PRV1 antibody, RGD1562941 antibody, CD177 antibody, MGC157159 antibody, 1190003K14Rik antibody, Pdp3 antibody, CD177 molecule antibody, CD177 antigen antibody, CD177 antibody, Cd177 antibody

Gene ID: 57126