CD63 antibody (APC)

Catalog No. ABIN536030

Product Details anti-CD63 Antibody (APC)

Target: CD63

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD63 antibody is conjugated to APC

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Mouse monoclonal antibody raised against native CD63.

Specificity: This antibody reacts with CD63 (LAMP-3), a 40-60 KDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.

Cross-Reactivity: Human

Immunogen: Native purified CD63 from human T cell line HPB-ALL.

Clone: MEM-259

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (10 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-CD63 antibody (APC) (ABIN536030)

Lin, Kamsteeg, Zhang, Jin, Sterling, Yue, Roos, Duffield, Spencer, Caplan, Wang: "Expression of tetraspan protein CD63 activates protein-tyrosine kinase (PTK) and enhances the PTK-induced inhibition of ROMK channels." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7674-81, (2008) (PubMed).

Kwon, Shin, Yim, Lee, Kang, Kim, Chung: "CD63 as a biomarker for predicting the clinical outcomes in adenocarcinoma of lung." in: Lung cancer (Amsterdam, Netherlands), Vol. 57, Issue 1, pp. 46-53, (2007) (PubMed).

Cerny, Feng, Yu, Miyake, Borgonovo, Klumperman, Meldolesi, McNeil, Kirchhausen: "The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing." in: EMBO reports, Vol. 5, Issue 9, pp. 883-8, (2004) (PubMed).

Target Details for CD63

Target: CD63

Alternative Name: CD63 (CD63 Products)

Synonyms: C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody

Gene ID: 967