CD72 antibody (CD72 Molecule) (PE)

Details for Product anti-CD72 Antibody No. ABIN536036
Antigen
  • CD72c
  • Ly-19
  • Ly-32
  • Ly-m19
  • Lyb-2
  • CD72b
  • LYB2
  • CD72 antigen
  • CD72 molecule
  • Cd72
  • CD72
Reactivity
Human
105
48
11
Host
Mouse
73
63
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD72 antibody is conjugated to PE
16
12
11
4
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP)
72
54
45
21
16
7
6
4
4
2
2
2
1
1
Options
Purpose Mouse monoclonal antibody raised against native CD72.
Immunogen Native purified CD72 from normal human lymphocytes from lymph node.
Clone 3F3
Isotype IgG2b
Specificity This antibody 3F3 reacts with CD72, a 39-43 KDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.
Plasmids, Primers & others Plasmids, Primers & others CD72 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD72 (CD72 Antibody Abstract)
Application Notes Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.2 % BSA, 0.09 % sodium azide)
Storage 4 °C
Storage Comment Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Product cited in: Mizrahi, Markel, Porgador, Bushkin, Mandelboim: "CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72." in: PLoS ONE, Vol. 2, Issue 9, pp. e818, 2007 (PubMed).

Kumanogoh, Shikina, Watanabe, Takegahara, Suzuki, Yamamoto, Takamatsu, Prasad, Mizui, Toyofuku, Tamura, Watanabe, Parnes, Kikutani: "Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment." in: International immunology, Vol. 17, Issue 10, pp. 1277-82, 2005 (PubMed).

Kumanogoh, Kikutani: "The CD100-CD72 interaction: a novel mechanism of immune regulation." in: Trends in immunology, Vol. 22, Issue 12, pp. 670-6, 2001 (PubMed).