SIT1 antibody (PE)

Catalog No. ABIN536098

Product Details anti-SIT1 Antibody (PE)

Target: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIT1 antibody is conjugated to PE

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against partial recombinant SIT1.

Specificity: This antibody reacts with SHP2-interacting transmembrane adaptor protein (SIT) expressed exclusively in lymphoid organs. It weakly crossreacts with mouse SIT.

Cross-Reactivity: Human

Immunogen: Recombinant protein corresponding to partial human SIT1.

Clone: SIT-01

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (1:50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-SIT1 antibody (PE) (ABIN536098)

Tedoldi, Paterson, Hansmann, Natkunam, Rüdiger, Angelisova, Du, Roberton, Roncador, Sanchez, Pozzobon, Masir, Barry, Pileri, Mason, Marafioti, Horejsí: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." in: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).

Hübener, Mincheva, Lichter, Schraven, Bruyns: "Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT)." in: Immunogenetics, Vol. 53, Issue 4, pp. 337-41, (2001) (PubMed).

Target Details for SIT1

Target: SIT1 (Signaling threshold Regulating Transmembrane Adaptor 1 (SIT1))

Alternative Name: SIT1 / SIT (SIT1 Products)

Synonyms: SIT1 antibody, RP11-331F9.5 antibody, SIT antibody, SIT-R antibody, Sit antibody, signaling threshold regulating transmembrane adaptor 1 antibody, suppression inducing transmembrane adaptor 1 antibody, SIT1 antibody, Sit1 antibody

Gene ID: 27240