Mouse monoclonal antibody raised against native FCGR3B.
Specificity
This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). This antibody reacts with CD16+ granulocytes.
FCGR3B
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.2 % BSA, 0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing.
Arase, Arase, Hirano, Yokosuka, Sakurai, Saito: "IgE-mediated activation of NK cells through Fc gamma RIII." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 6, pp. 3054-8, (2003) (PubMed).
Target
FCGR3B
(Fc Fragment of IgG, Low Affinity IIIb, Receptor (CD16b) (FCGR3B))