ICAM-3/CD50 antibody (PE)

Catalog No. ABIN536603

Product Details anti-ICAM-3/CD50 Antibody (PE)

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM-3/CD50 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against native ICAM3.

Specificity: This antibody MEM-171 recognizes an epitope in the D2 domain of CD50 (ICAM-3), a 120-130 KDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells, it is negative on platelets and erythrocytes.

Cross-Reactivity: Human

Immunogen: Native purified ICAM3 from human granulocytes.

Clone: MEM-171

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-ICAM-3/CD50 antibody (PE) (ABIN536603)

Bogoevska, Nollau, Lucka, Grunow, Klampe, Uotila, Samsen, Gahmberg, Wagener: "DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues." in: Glycobiology, Vol. 17, Issue 3, pp. 324-33, (2007) (PubMed).

Target Details for ICAM-3/CD50

Target: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Alternative Name: CD50 / ICAM3 (ICAM3 Products)

Synonyms: CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody

Gene ID: 3385