DcR2 antibody (AA 1-210) (FITC)

Catalog No. ABIN536704

Product Details anti-DcR2 Antibody (FITC)

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Binding Specificity: AA 1-210

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DcR2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Purpose: Mouse monoclonal antibody raised against partial recombinant TNFRSF10D.

Specificity: This antibody reacts with TRAIL-R4, a 42 KDa transmembrane protein expressed on various blood cells.

Cross-Reactivity: Human

Immunogen: Recombinant Fc fusion protein corresponding to amino acids 1-210 of TNFRSF10D.

Clone: TRAIL-R4-01

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry (3 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

References for anti-DcR2 antibody (FITC) (ABIN536704)

Falschlehner, Emmerich, Gerlach, Walczak: "TRAIL signalling: decisions between life and death." in: The international journal of biochemistry & cell biology, Vol. 39, Issue 7-8, pp. 1462-75, (2007) (PubMed).

Deligezer, Dalay: "Expression of the TRAIL receptors in blood mononuclear cells in leukemia." in: Pathology oncology research : POR, Vol. 13, Issue 4, pp. 290-4, (2007) (PubMed).

Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: "Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2." in: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7046-55, (2006) (PubMed).

Target Details for DcR2

Target: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Alternative Name: CD264 / TRAILR4 (TNFRSF10D Products)

Synonyms: TNFRSF10D antibody, CD264 antibody, DCR2 antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, TNF receptor superfamily member 10d antibody, tumor necrosis factor receptor superfamily member 10D antibody, TNFRSF10D antibody, LOC716901 antibody

Gene ID: 8793

Pathways: Apoptosis