TICAM1 antibody (AA 143-158)

Catalog No. ABIN537469

Product Details anti-TICAM1 Antibody

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Binding Specificity: AA 143-158

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TICAM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Ticam1.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to amino acids 143-158 of mouse Ticam1.

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.2 % gelatin, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TICAM1 antibody (ABIN537469)

Gabhann, Higgs, Brennan, Thomas, Damen, Ben Larbi, Krystal, Jefferies: "Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2314-20, (2010) (PubMed).

Chassin, Goujon, Darche, du Merle, Bens, Cluzeaud, Werts, Ogier-Denis, Le Bouguénec, Buzoni-Gatel, Vandewalle: "Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 7, pp. 4773-84, (2006) (PubMed).

Naiki, Michelsen, Zhang, Chen, Doherty, Arditi: "Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5491-5, (2005) (PubMed).

Target Details for TICAM1

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Alternative Name: TICAM1 / TRIF (TICAM1 Products)

Synonyms: IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody

Gene ID: 148022

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades