STAT5A antibody (pTyr694)

Catalog No. ABIN537768

Product Details anti-STAT5A Antibody

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Binding Specificity: pTyr694

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT5A.

Cross-Reactivity: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y694 of human STAT5A.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-STAT5A antibody (ABIN537768)

Sekine, Yamamoto, Yumioka, Sugiyama, Tsuji, Oritani, Shimoda, Minoguchi, Yoshimura, Matsuda: "Physical and functional interactions between STAP-2/BKS and STAT5." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8188-96, (2005) (PubMed).

Martens, Uzan, Wery, Hooghe, Hooghe-Peters, Gertler: "Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13817-23, (2005) (PubMed).

Defilippi, Rosso, Dentelli, Calvi, Garbarino, Tarone, Pegoraro, Brizzi: "{beta}1 Integrin and IL-3R coordinately regulate STAT5 activation and anchorage-dependent proliferation." in: The Journal of cell biology, Vol. 168, Issue 7, pp. 1099-108, (2005) (PubMed).

Target Details for STAT5A

Target: STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))

Alternative Name: STAT5 / STAT5A (STAT5A Products)

Synonyms: MGF antibody, STAT5 antibody, AA959963 antibody, Stat5 antibody, STAT5A/MGF antibody, STATA5 antibody, STAT5A antibody, stat5 antibody, stat5b antibody, signal transducer and activator of transcription 5A antibody, signal transducer and activator of transcription 5a antibody, STAT5A antibody, Stat5a antibody, stat5a antibody, LOC100348518 antibody, LOC100716811 antibody

Gene ID: 6776

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation