SIRT1 antibody (C-Term)
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- Target See all SIRT1 Antibodies
- SIRT1 (Sirtuin 1 (SIRT1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIRT1 antibody is un-conjugated
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Application
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Purpose
- Rabbit polyclonal antibody raised against a synthetic peptide of SIRT1.
- Cross-Reactivity
- Human
- Immunogen
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SIRT1.
- Top Product
- Discover our top product SIRT1 Primary Antibody
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- Application Notes
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Western Blot (1:400)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In PBS (0.2 % gelatin, 0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C. Do not freeze.
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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing." in: Nature genetics, Vol. 39, Issue 2, pp. 237-42, (2007) (PubMed).
: "Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation." in: PLoS genetics, Vol. 2, Issue 3, pp. e40, (2006) (PubMed).
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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing." in: Nature genetics, Vol. 39, Issue 2, pp. 237-42, (2007) (PubMed).
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- Target
- SIRT1 (Sirtuin 1 (SIRT1))
- Alternative Name
- SIRT1 (SIRT1 Products)
- Synonyms
- sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
- Gene ID
- 23411
- Pathways
- MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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