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SIRT1 antibody (C-Term)

SIRT1 Reactivity: Human WB, ChIP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN538018
  • Target See all SIRT1 Antibodies
    SIRT1 (Sirtuin 1 (SIRT1))
    Binding Specificity
    • 27
    • 16
    • 16
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 141
    • 88
    • 57
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 127
    • 20
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 111
    • 41
    Polyclonal
    Conjugate
    • 73
    • 14
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    Application
    • 124
    • 50
    • 50
    • 41
    • 39
    • 35
    • 26
    • 23
    • 20
    • 14
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Purpose
    Rabbit polyclonal antibody raised against a synthetic peptide of SIRT1.
    Cross-Reactivity
    Human
    Immunogen
    A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SIRT1.
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • Application Notes
    Western Blot (1:400)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.2 % gelatin, 0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze.
  • Ohm, McGarvey, Yu, Cheng, Schuebel, Cope, Mohammad, Chen, Daniel, Yu, Berman, Jenuwein, Pruitt, Sharkis, Watkins, Herman, Baylin: "A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing." in: Nature genetics, Vol. 39, Issue 2, pp. 237-42, (2007) (PubMed).

    Pruitt, Zinn, Ohm, McGarvey, Kang, Watkins, Herman, Baylin: "Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation." in: PLoS genetics, Vol. 2, Issue 3, pp. e40, (2006) (PubMed).

  • Target
    SIRT1 (Sirtuin 1 (SIRT1))
    Alternative Name
    SIRT1 (SIRT1 Products)
    Synonyms
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    Gene ID
    23411
    Pathways
    MAPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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