PNKP antibody (Internal Region)

Catalog No. ABIN539464

Product Details anti-PNKP Antibody

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNKP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PNKP.

Cross-Reactivity: Chimpanzee, Dog, Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to internal region of human PNKP.

Application Details

Application Notes: ELISA (1:3000-1:12000)
Western Blot (1:300-1:1500)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PNKP antibody (ABIN539464)

Mani, Karimi-Busheri, Fanta, Cass, Weinfeld: "Spectroscopic studies of DNA and ATP binding to human polynucleotide kinase: evidence for a ternary complex." in: Biochemistry, Vol. 42, Issue 41, pp. 12077-84, (2003) (PubMed).

Chappell, Hanakahi, Karimi-Busheri, Weinfeld, West: "Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining." in: The EMBO journal, Vol. 21, Issue 11, pp. 2827-32, (2002) (PubMed).

Target Details for PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Alternative Name: PNKP (PNKP Products)

Synonyms: EIEE10 antibody, MCSZ antibody, PNK antibody, Tb06.28P18.320 antibody, 21.m03011 antibody, 1810009G08Rik antibody, polynucleotide kinase 3'-phosphatase antibody, hypothetical protein antibody, polynucleotide kinase 3'- phosphatase antibody, PNKP antibody, Pnkp antibody, Tc00.1047053507017.50 antibody, Tc00.1047053505807.190 antibody, Tb927.6.1580 antibody, BBOV_IV000690 antibody, CC1G_05202 antibody, PGTG_20262 antibody, PGTG_18987 antibody, pnkp.S antibody, pnkp antibody

Gene ID: 11284

Pathways: DNA Damage Repair, Nucleotide Phosphorylation