PKC beta antibody (Internal Region)

Catalog No. ABIN539471

Product Details anti-PKC beta Antibody

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Monkey, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PRKCB.

Cross-Reactivity: Cow, Human, Monkey, Mouse, Rabbit, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to internal region of human PRKCB.

Application Details

Application Notes: ELISA (1:75000-1:80000)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PKC beta antibody (ABIN539471)

Nakura, Higuchi, Yoshida, Yoshikawa: "PKC? suppresses osteoblastic differentiation." in: Bone, Vol. 48, Issue 3, pp. 476-84, (2011) (PubMed).

Graff, McNulty, Hanna, Konicek, Lynch, Bailey, Banks, Capen, Goode, Lewis, Sams, Huss, Campbell, Iversen, Neubauer, Brown, Musib, Geeganage, Thornton et al.: "The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma ..." in: Cancer research, Vol. 65, Issue 16, pp. 7462-9, (2005) (PubMed).

Koivunen, Aaltonen, Koskela, Lehenkari, Laato, Peltonen: "Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells." in: Cancer research, Vol. 64, Issue 16, pp. 5693-701, (2004) (PubMed).

Target Details for PKC beta

Target: PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

Alternative Name: PRKCB (PRKCB Products)

Synonyms: PKC-beta antibody, PKCB antibody, PRKCB1 antibody, PRKCB2 antibody, A130082F03Rik antibody, PKC-Beta antibody, Pkcb antibody, Prkcb1 antibody, Prkcb2 antibody, PKC-B antibody, Prkcb antibody, prkcb1 antibody, zgc:63591 antibody, PKC antibody, PRKCB_tv2 antibody, Pkc53E antibody, prkcb1l antibody, zgc:64063 antibody, protein kinase C beta antibody, protein kinase C, beta antibody, protein kinase C, beta b antibody, protein kinase C, beta a antibody, PRKCB antibody, Prkcb antibody, prkcbb antibody, prkcba antibody

Gene ID: 5579

Pathways: WNT Signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling