SMAD4 antibody (C-Term)

Catalog No. ABIN539486

Product Details anti-SMAD4 Antibody

Target: SMAD4 (SMAD Family Member 4 (SMAD4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Frog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of SMAD4.

Cross-Reactivity: Frog, Human, Mouse

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to C-terminus of human SMAD4.

Application Details

Application Notes: ELISA (1:15000-1:60000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-SMAD4 antibody (ABIN539486)

Karlsson, Blank, Moody, Ehinger, Singbrant, Deng, Karlsson: "Smad4 is critical for self-renewal of hematopoietic stem cells." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 467-74, (2007) (PubMed).

Wang, Kim, Lee, Choi, Kim, Park, Hong, Wu, Shin: "Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 1, pp. 102-10, (2007) (PubMed).

Lim, Hoffmann: "Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18580-5, (2006) (PubMed).

Target Details for SMAD4

Target: SMAD4 (SMAD Family Member 4 (SMAD4))

Alternative Name: SMAD4 (SMAD4 Products)

Synonyms: smad4 antibody, DPC4 antibody, JIP antibody, MADH4 antibody, MYHRS antibody, AW743858 antibody, D18Wsu70e antibody, Madh4 antibody, XSmad4alpha antibody, Xsmad4 antibody, dpc4 antibody, jip antibody, madh4 antibody, xsmad4a antibody, SMAD family member 4 antibody, Smad4 protein antibody, SMAD family member 4, gene 1 L homeolog antibody, SMAD4 antibody, smad4 antibody, Smad4 antibody, smad4.1.L antibody

Gene ID: 4089

Pathways: Cell Division Cycle, Chromatin Binding, Autophagy