THRA antibody (N-Term)

Catalog No. ABIN539498

Product Details anti-THRA Antibody

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of THRA.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to N-terminus of human THRA.

Application Details

Application Notes: ELISA (1:650000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-THRA antibody (ABIN539498)

Ying, Araki, Furuya, Kato, Cheng: "Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor." in: Molecular and cellular biology, Vol. 27, Issue 6, pp. 2359-71, (2007) (PubMed).

Nascimento, Dias, Nunes, Aparício, Ambrosio, Bleicher, Figueira, Santos, de Oliveira Neto, Fischer, Togashi, Craievich, Garratt, Baxter, Webb, Polikarpov: "Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function." in: Journal of molecular biology, Vol. 360, Issue 3, pp. 586-98, (2006) (PubMed).

Wan, Farboud, Privalsky: "Pituitary resistance to thyroid hormone syndrome is associated with T3 receptor mutants that selectively impair beta2 isoform function." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 6, pp. 1529-42, (2005) (PubMed).

Target Details for THRA

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Alternative Name: THRA / ERBA1 (THRA Products)

Synonyms: AR7 antibody, CHNG6 antibody, EAR7 antibody, ERB-T-1 antibody, ERBA antibody, ERBA1 antibody, NR1A1 antibody, THRA1 antibody, THRA2 antibody, c-ERBA-1 antibody, C-ERBA-ALPHA antibody, TRalpha antibody, c-erba antibody, erba antibody, nr1a1-A antibody, thra-A antibody, thra1 antibody, TR[a]1 antibody, nr1a1 antibody, thra antibody, thral antibody, tra antibody, tra1 antibody, wu:fb59g07 antibody, Thra1 antibody, 6430529J03Rik antibody, AW259572 antibody, Erba antibody, Nr1a1 antibody, Rvr antibody, T3R[a] antibody, T3Ralpha antibody, Thra2 antibody, C-ERBA ALPHA1 antibody, Thra antibody, fTHRalphaA antibody, nr1a1-a antibody, thyroid hormone receptor, alpha antibody, thyroid hormone receptor, alpha L homeolog antibody, thyroid hormone receptor alpha a antibody, thyroid hormone receptor alpha antibody, thyroid hormone receptor alpha-A antibody, THRA antibody, thra.L antibody, thraa antibody, Thra antibody, tr-alpha antibody, LOC109641414 antibody

Gene ID: 7067

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development