FTL antibody (C-Term)

Catalog No. ABIN539690

Product Details anti-FTL Antibody

Target: FTL (Ferritin, Light Polypeptide (FTL))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Goat polyclonal antibody raised against synthetic peptide of FTL.

Sequence: C-GEYLFERLTL KHD

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to C-terminus of human FTL.

Application Details

Application Notes: ELISA (1:4000)
Western Blot (0.1-0.3 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-6 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In Tris saline, pH 7.3 (0.5 % BSA, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-FTL antibody (ABIN539690)

Gao, Du, Hua, Keep, Strahle, Xi: "Role of red blood cell lysis and iron in hydrocephalus after intraventricular hemorrhage." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 34, Issue 6, pp. 1070-5, (2014) (PubMed).

Guo, Chen, Tang, Zhang, Tao, Li, Zhu, Feng, Chen: "Minocycline-induced attenuation of iron overload and brain injury after experimental germinal matrix hemorrhage." in: Brain research, Vol. 1594, pp. 115-24, (2014) (PubMed).

Hatakeyama, Okauchi, Hua, Keep, Xi: "Deferoxamine reduces neuronal death and hematoma lysis after intracerebral hemorrhage in aged rats." in: Translational stroke research, Vol. 4, Issue 5, pp. 546-53, (2013) (PubMed).

Leonardo, Agrawal, Singh, Moore, Biswal, Doré: "Oral administration of the flavanol (-)-epicatechin bolsters endogenous protection against focal ischemia through the Nrf2 cytoprotective pathway." in: The European journal of neuroscience, Vol. 38, Issue 11, pp. 3659-68, (2013) (PubMed).

Hagemann, Jobe, Messing: "Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival." in: PLoS ONE, Vol. 7, Issue 5, pp. e37304, (2012) (PubMed).

Wu, Bao, Xi, Keep, Thompson, Hua: "Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats." in: Journal of neurosurgery, Vol. 114, Issue 6, pp. 1805-11, (2011) (PubMed).

Chen, Gao, Hua, Keep, Muraszko, Xi: "Role of iron in brain injury after intraventricular hemorrhage." in: Stroke; a journal of cerebral circulation, Vol. 42, Issue 2, pp. 465-70, (2011) (PubMed).

Sammarco, Ditch, Banerjee, Grabczyk: "Ferritin L and H subunits are differentially regulated on a post-transcriptional level." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4578-87, (2008) (PubMed).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: Ferritin light chain (FTL) (FTL Products)

Synonyms: NBIA3 antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, FT antibody, Ftl antibody, Ftl-1 antibody, L-ferritin antibody, FTL antibody, Ftl1 antibody, FTL2 antibody, FTD antibody, ferritin light chain antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin light polypeptide 1 antibody, ferritin, light polypeptide antibody, ferritin light-chain antibody, ferritin light chain 1 antibody, FTL antibody, fth1.L antibody, Ftl1 antibody, CpipJ_CPIJ004069 antibody, Ftl antibody

Gene ID: 2512

Pathways: Transition Metal Ion Homeostasis