NUMB antibody (AA 600-653)

Catalog No. ABIN540356

Product Details anti-NUMB Antibody

Target: NUMB (Numb Homolog (NUMB))

Binding Specificity: AA 600-653

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Numb.

Specificity: This antibody is specific to all four isoforms of the Numb protein.

Cross-Reactivity: Chicken, Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to C-terminus amino acids 600-653 of mouse Numb.

Application Details

Application Notes: Western Blot (0.2-0.5 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-NUMB antibody (ABIN540356)

Santolini, Puri, Salcini, Gagliani, Pelicci, Tacchetti, Di Fiore: "Numb is an endocytic protein." in: The Journal of cell biology, Vol. 151, Issue 6, pp. 1345-52, (2001) (PubMed).

Schaefer, Petronczki, Dorner, Forte, Knoblich: "Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system." in: Cell, Vol. 107, Issue 2, pp. 183-94, (2001) (PubMed).

Dho, French, Woods, McGlade: "Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain." in: The Journal of biological chemistry, Vol. 274, Issue 46, pp. 33097-104, (2000) (PubMed).

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB (NUMB Products)

Synonyms: C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody

Gene ID: 18222

Pathways: Cell-Cell Junction Organization