MAP1LC3A antibody (AA 1-100)

Catalog No. ABIN540679

Product Details anti-MAP1LC3A Antibody

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Binding Specificity: AA 1-100

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of MAP1LC3A.

Specificity: This antibody is specific to LC3.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to amino acids 1-100 of human MAP1LC3A.

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400)
Immunoprecipitation (20 μg/500 μg of protein)
Western Blot (2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-MAP1LC3A antibody (ABIN540679)

Panyasrivanit, Khakpoor, Wikan, Smith: "Co-localization of constituents of the dengue virus translation and replication machinery with amphisomes." in: The Journal of general virology, Vol. 90, Issue Pt 2, pp. 448-56, (2009) (PubMed).

Miller, Zhao, Stephenson, Cadwell, Pua, Lee, Mizushima, Iwasaki, He, Swat, Virgin: "The autophagy gene ATG5 plays an essential role in B lymphocyte development." in: Autophagy, Vol. 4, Issue 3, pp. 309-14, (2008) (PubMed).

Zhang, Bosch-Marce, Shimoda, Tan, Baek, Wesley, Gonzalez, Semenza: "Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10892-903, (2008) (PubMed).

Cadwell, Liu, Brown, Miyoshi, Loh, Lennerz, Kishi, Kc, Carrero, Hunt, Stone, Brunt, Xavier, Sleckman, Li, Mizushima, Stappenbeck, Virgin: "A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells." in: Nature, Vol. 456, Issue 7219, pp. 259-63, (2008) (PubMed).

Humbey, Pimkina, Zilfou, Jarnik, Dominguez-Brauer, Burgess, Eischen, Murphy: "The ARF tumor suppressor can promote the progression of some tumors." in: Cancer research, Vol. 68, Issue 23, pp. 9608-13, (2008) (PubMed).

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: MAP1LC3A (MAP1LC3A Products)

Synonyms: ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody

Gene ID: 84557

Pathways: Autophagy