LOX antibody (AA 200-300, AA 300-400)

Catalog No. ABIN540694

Product Details anti-LOX Antibody

Target: LOX (Lysyl Oxidase (LOX))

Binding Specificity: AA 200-300, AA 300-400

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Pig, Chicken, Cow, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of LOX.

Cross-Reactivity: Chicken, Cow, Human, Mouse, Pig, Rat, Xenopus laevis, Zebrafish (Danio rerio)

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A mixture of synthetic peptides corresponding to residues within 300-400 and 200-300 of human LOX.

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-LOX antibody (ABIN540694)

Osawa, Ohga, Akiyama, Hida, Kitayama, Kawamoto, Yamamoto, Maishi, Kondoh, Onodera, Fujie, Shinohara, Nonomura, Shindoh, Hida: "Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis." in: British journal of cancer, Vol. 109, Issue 8, pp. 2237-47, (2013) (PubMed).

Tanaka, Yamaguchi, Shoji, Nangaku: "Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 34866-82, (2012) (PubMed).

Erler, Bennewith, Nicolau, Dornhöfer, Kong, Le, Chi, Jeffrey, Giaccia: "Lysyl oxidase is essential for hypoxia-induced metastasis." in: Nature, Vol. 440, Issue 7088, pp. 1222-6, (2006) (PubMed).

Thomassin, Werneck, Broekelmann, Gleyzal, Hornstra, Mecham, Sommer: "The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers." in: The Journal of biological chemistry, Vol. 280, Issue 52, pp. 42848-55, (2005) (PubMed).

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: Lysyl oxidase (LOX Products)

Synonyms: LOX antibody, Xlox antibody, MGC146507 antibody, lox antibody, zgc:77447 antibody, AI893619 antibody, TSC-160 antibody, H-rev142 antibody, Rrg1 antibody, lysyl oxidase antibody, lysyl oxidase a antibody, lysyl oxidase L homeolog antibody, LOX antibody, lox antibody, loxa antibody, lox.L antibody, Lox antibody

Gene ID: 4015

Pathways: SARS-CoV-2 Protein Interactome