ATM antibody (C-Term)

Catalog No. ABIN540777

Product Details anti-ATM Antibody

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Rabbit polyclonal antibody raised against partial recombinant ATM.

Specificity: This antibody is specific to ATM.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to C-terminus of human ATM.

Application Details

Application Notes: The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (50 % glycerol, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-ATM antibody (ABIN540777)

Vissinga, Yeo, Warren, Brawley, Phillips, Cerosaletti, Concannon: "Nuclear export of NBN is required for normal cellular responses to radiation." in: Molecular and cellular biology, Vol. 29, Issue 4, pp. 1000-6, (2009) (PubMed).

Gruhne, Sompallae, Marescotti, Kamranvar, Gastaldello, Masucci: "The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 7, pp. 2313-8, (2009) (PubMed).

Hovest, Brüggenolte, Hosseini, Krieg, Herrmann: "Senescence of human fibroblasts after psoralen photoactivation is mediated by ATR kinase and persistent DNA damage foci at telomeres." in: Molecular biology of the cell, Vol. 17, Issue 4, pp. 1758-67, (2006) (PubMed).

Yang, Jeong, Brown, Lee, Pandolfi, Chung, Kim: "Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26645-54, (2006) (PubMed).

Lovejoy, Lock, Yenamandra, Cortez: "DDB1 maintains genome integrity through regulation of Cdt1." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 7977-90, (2006) (PubMed).

Target Details for ATM

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Alternative Name: ATM (ATM Products)

Synonyms: ATM antibody, Atm antibody, CG6535 antibody, Dmel\\CG6535 antibody, Tefu antibody, atm antibody, atm/tefu antibody, dATM antibody, tef antibody, Xatm antibody, at1 antibody, atdc antibody, tel1 antibody, telo1 antibody, AT1 antibody, ATA antibody, ATC antibody, ATD antibody, ATDC antibody, ATE antibody, TEL1 antibody, TELO1 antibody, AI256621 antibody, C030026E19Rik antibody, telomere fusion antibody, ATM serine/threonine kinase L homeolog antibody, ATM serine/threonine kinase antibody, ataxia telangiectasia mutated antibody, ataxia telangiectasia mutated (atm) antibody, serine/threonine-protein kinase ATM antibody, tefu antibody, atm.L antibody, atm antibody, ATM antibody, EDI_100660 antibody, CpipJ_CPIJ001772 antibody, BDBG_08252 antibody, PAAG_02532 antibody, MCYG_05088 antibody, VDBG_06833 antibody, ACLA_015700 antibody, LOC5565620 antibody, MGYG_07634 antibody, PGTG_14279 antibody, Atm antibody

Gene ID: 472

Pathways: p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus