ABCA1
Reactivity: Mouse, Human, Rat, Guinea Pig, Dog
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Flow Cytometry (1:400) Immunocytochemistry (1:100) Immunofluorescence (1:100) Immunohistochemistry (1:200) Immunoprecipitation (1:10-1:500) Western Blot (1:500) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.05 % sodium azide).
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for short term. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Nakanishi, Vikstedt, Söderlund, Lee-Rueckert, Hiukka, Ehnholm, Muilu, Metso, Naukkarinen, Palotie, Kovanen, Jauhiainen, Taskinen: "Serum, but not monocyte macrophage foam cells derived from low HDL-C subjects, displays reduced cholesterol efflux capacity." in: Journal of lipid research, Vol. 50, Issue 2, pp. 183-92, (2009) (PubMed).
Nandi, Ma, Denis, Karwatsky, Li, Jiang, Zha: "ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity." in: Journal of lipid research, Vol. 50, Issue 3, pp. 456-66, (2009) (PubMed).
Dang, Liu, Pang, Li, Wang, Shyy, Zhu: "Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6218-26, (2009) (PubMed).
Bhatnagar, Damron, Hillgartner: "Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 10023-33, (2009) (PubMed).
Henry-Berger, Mouzat, Baron, Bernabeu, Marceau, Saru, Sapin, Lobaccaro, Caira: "Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR." in: Biology of reproduction, Vol. 78, Issue 6, pp. 968-75, (2008) (PubMed).
Target
ABCA1
(ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))