AANAT antibody

Catalog No. ABIN540804

Product Details anti-AANAT Antibody

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AANAT antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against AANAT.

Specificity: This antibody is specific to primate AANAT.

Cross-Reactivity: Human, Monkey, Primate

Characteristics: Antibody Reactive Against AANAT.

Immunogen: Human AANAT.

Application Details

Application Notes: Western Blot (1:500-1:1000)
Immunocytochemistry (1:200)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.1 % BSA, 0.05 % thimerosal)

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-AANAT antibody (ABIN540804)

Klein: "Arylalkylamine N-acetyltransferase: "the Timezyme"." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 4233-7, (2007) (PubMed).

Klein, Ganguly, Coon, Weller, Obsil, Hickman, Dyda: "14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin." in: Biochemical Society transactions, Vol. 30, Issue 4, pp. 365-73, (2002) (PubMed).

Iuvone, Brown, Haque, Weller, Zawilska, Chaurasia, Ma, Klein: "Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase." in: Investigative ophthalmology & visual science, Vol. 43, Issue 2, pp. 564-72, (2002) (PubMed).

Coon, Del Olmo, Young, Klein: "Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87)." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4699-706, (2002) (PubMed).

Coon, Weller, Korf, Namboodiri, Rollag, Klein: "cAmp regulation of arylalkylamine N-acetyltransferase (AANAT, EC 2.3.1.87): a new cell line (1E7) provides evidence of intracellular AANAT activation." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24097-107, (2001) (PubMed).

Target Details for AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Alternative Name: Serotonin Acetylase (AANAT Products)

Synonyms: DSPS antibody, SNAT antibody, AA-NAT antibody, Nat4 antibody, Nat-2 antibody, Snat antibody, aralkylamine N-acetyltransferase antibody, arylalkylamine N-acetyltransferase antibody, AANAT antibody, Aanat antibody

Gene ID: 15

Pathways: Photoperiodism