HPGD antibody

Catalog No. ABIN540849

Product Details anti-HPGD Antibody

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Rabbit polyclonal antibody raised against HPGD.

Specificity: This antibody is specific to 15-PGDH.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against HPGD.

Immunogen: Human HPGD.

Application Details

Application Notes: Western Blot (1:5000-1:6000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In Tris-glycine, 150 mM NaCl (0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-HPGD antibody (ABIN540849)

Mann, Backlund, Buchanan, Daikoku, Holla, Rosenberg, Dey, DuBois: "Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression." in: Cancer research, Vol. 66, Issue 13, pp. 6649-56, (2006) (PubMed).

Backlund, Mann, Holla, Buchanan, Tai, Musiek, Milne, Katkuri, DuBois: "15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer." in: The Journal of biological chemistry, Vol. 280, Issue 5, pp. 3217-23, (2005) (PubMed).

Ding, Tong, Liu, Moscow, Tai: "NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer." in: Carcinogenesis, Vol. 26, Issue 1, pp. 65-72, (2004) (PubMed).

Yan, Rerko, Platzer, Dawson, Willis, Tong, Lawrence, Lutterbaugh, Lu, Willson, Luo, Hensold, Tai, Wilson, Markowitz: "15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17468-73, (2004) (PubMed).

Giannoulias, Patel, Holloway, Lye, Tai, Challis: "Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 3, pp. 1345-52, (2002) (PubMed).

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: HPGD (HPGD Products)

Synonyms: CBR antibody, SDR21C1 antibody, hCBR1 antibody, 15-PGDH antibody, PGDH antibody, PGDH1 antibody, PHOAR1 antibody, SDR36C1 antibody, MGC80546 antibody, MGC79454 antibody, AV026552 antibody, carbonyl reductase 1 antibody, 15-hydroxyprostaglandin dehydrogenase antibody, hydroxyprostaglandin dehydrogenase 15-(NAD) antibody, 15-hydroxyprostaglandin dehydrogenase L homeolog antibody, hydroxyprostaglandin dehydrogenase 15 (NAD) antibody, CBR1 antibody, HPGD antibody, hpgd.L antibody, hpgd antibody, pgdh antibody, Hpgd antibody, PTRG_03214 antibody, VDBG_09957 antibody

Gene ID: 3248