Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purpose
Rabbit polyclonal antibody raised against synthetic peptide of TP53INP1.
Specificity
This sequence is identical between a and b forms of the PUMA proteins. A band at 27 KDa can be detected. A lower band at 18 KDa was detected in human spleen, and mouse liver and kidney tissue lysates, which may represent the p53DINP1-b form. It is human, mouse, and rat reactive.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human TP53INP1.
Tomasini, Samir, Vaccaro, Pebusque, Dagorn, Iovanna, Dusetti: "Molecular and functional characterization of the stress-induced protein (SIP) gene and its two transcripts generated by alternative splicing. SIP induced by stress and promotes cell death." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 44185-92, (2001) (PubMed).
Target
TP53INP1
(Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))