NOD2 antibody (Nucleotide-Binding Oligomerization Domain Containing 2)

Details for Product anti-NOD2 Antibody No. ABIN541424
Target
Reactivity
Human
56
22
18
Host
Rabbit
47
7
6
1
Clonality
Polyclonal
Conjugate
This NOD2 antibody is un-conjugated
5
4
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
45
24
15
14
13
13
6
5
4
2
2
2
1
1
Options
Purpose Rabbit polyclonal antibody raised against synthetic peptide of NOD2.
Immunogen A synthetic peptide corresponding to N-terminus 16 amino acids of human NOD2.
Specificity NOD2 has no cross-reaction with NOD1.
Target
Alternative Name CARD15 / NOD2 (NOD2 Antibody Abstract)
Pathways Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
Application Notes Western Blot (2-4 μg/mL)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.02 % sodium azide)
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Images
Image no. 1 for anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibody (ABIN541424) Western blot analysis of NOD2 in Jurkat cell lysate with NOD2 polyclonal antibody at...
Image no. 2 for anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibody (ABIN541424) Immunocytochemistry of NOD2 in Jurkat cells with NOD2 polyclonal antibody at 5 ug/mL .
Product cited in: Hugot, Chamaillard, Zouali, Lesage, Cézard, Belaiche, Almer, Tysk, OMorain, Gassull, Binder, Finkel, Cortot, Modigliani, Laurent-Puig, Gower-Rousseau, Macry, Colombel, Sahbatou, Thomas: "Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease." in: Nature, Vol. 411, Issue 6837, pp. 599-603, 2001 (PubMed).

Ogura, Bonen, Inohara, Nicolae, Chen, Ramos, Britton, Moran, Karaliuskas, Duerr, Achkar, Brant, Bayless, Kirschner, Hanauer, Nuñez, Cho: "A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease." in: Nature, Vol. 411, Issue 6837, pp. 603-6, 2001 (PubMed).