IFIH1 antibody (C-Term)

Catalog No. ABIN541582

Product Details anti-IFIH1 Antibody

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of IFIH1.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide corresponding to C-terminus 16 amino acids of human IFIH1.

Application Details

Application Notes: Western Blot (1-2 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-IFIH1 antibody (ABIN541582)

Akira, Uematsu, Takeuchi: "Pathogen recognition and innate immunity." in: Cell, Vol. 124, Issue 4, pp. 783-801, (2006) (PubMed).

Hiscott, Nguyen, Arguello, Nakhaei, Paz: "Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses." in: Oncogene, Vol. 25, Issue 51, pp. 6844-67, (2006) (PubMed).

Andrejeva, Childs, Young, Carlos, Stock, Goodbourn, Randall: "The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 49, pp. 17264-9, (2004) (PubMed).

Target Details for IFIH1

Target: IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

Alternative Name: Helicard (IFIH1 Products)

Synonyms: MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody

Gene ID: 64135

Pathways: Activation of Innate immune Response