NR1H3 antibody (C-Term)

Catalog No. ABIN542003

Product Details anti-NR1H3 Antibody

Target: NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1H3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of NR1H3.

Specificity: Identical to the related rat and mouse sequence.

Cross-Reactivity: Human, Mouse, Rat

Immunogen: A synthetic peptide corresponding to amino acids at C-terminus of human NR1H3.

Isotype: IgG

Application Details

Application Notes: Western Blot (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 0.9 mg NaCl, 0.2 mg Na₂HPO₄ (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-NR1H3 antibody (ABIN542003)

Zelcer, Hong, Boyadjian, Tontonoz: "LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor." in: Science (New York, N.Y.), Vol. 325, Issue 5936, pp. 100-4, (2009) (PubMed).

Mitro, Mak, Vargas, Godio, Hampton, Molteni, Kreusch, Saez: "The nuclear receptor LXR is a glucose sensor." in: Nature, Vol. 445, Issue 7124, pp. 219-23, (2007) (PubMed).

Joseph, Castrillo, Laffitte, Mangelsdorf, Tontonoz: "Reciprocal regulation of inflammation and lipid metabolism by liver X receptors." in: Nature medicine, Vol. 9, Issue 2, pp. 213-9, (2003) (PubMed).

Target Details for NR1H3

Target: NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))

Alternative Name: NR1H3 (NR1H3 Products)

Synonyms: NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody

Gene ID: 10062

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C