APP antibody

Catalog No. ABIN542621

Product Details anti-APP Antibody

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of App.

Sequence: HMNVQNGKWE SDPSGTKTC

Cross-Reactivity: Rat

Purification: Purified

Immunogen: A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 44-62 of mouse App.

Application Details

Application Notes: Immunohistochemistry (1:500-1:3000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Lyophilized from PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-APP antibody (ABIN542621)

Guénette: "Mechanisms of Abeta clearance and catabolism." in: Neuromolecular medicine, Vol. 4, Issue 3, pp. 147-60, (2004) (PubMed).

Wilson, Doms, Lee: "Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production." in: Journal of neuroscience research, Vol. 74, Issue 3, pp. 361-9, (2003) (PubMed).

Andreasen, Sjögren, Blennow: "CSF markers for Alzheimer's disease: total tau, phospho-tau and Abeta42." in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, Vol. 4, Issue 4, pp. 147-55, (2003) (PubMed).

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: App (APP Products)

Synonyms: AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, APP antibody, APP-like antibody, APPL antibody, Abeta antibody, BcDNA:GH04413 antibody, CG7727 antibody, Dmel\\CG7727 antibody, EG:65F1.5 antibody, appl antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, app antibody, wu:fj34d10 antibody, wu:fk65e12 antibody, zgc:85740 antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, beta amyloid protein precursor-like antibody, amyloid beta (A4) precursor protein a antibody, amyloid beta precursor protein L homeolog antibody, APP antibody, app antibody, Appl antibody, App antibody, appa antibody, app.L antibody

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour