MBP antibody (AA 68-86)

Catalog No. ABIN542629

Product Details anti-MBP Antibody

Target: MBP (Myelin Basic Protein (MBP))

Binding Specificity: AA 68-86

Reactivity: Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of MBP.

Sequence: YGSLPQKSQR SQDENPVV

Specificity: This antiserum recognizes MBP in demyelinated nerve tissues. Immunohistochemical analysis of lesioned rat spinal cord indictaes a high level of specificity for this antiserum.

Cross-Reactivity: Guinea Pig, Human, Rat

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 68-86 of guinea pig MBP.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (1:1000-1:4000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from PBS

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-MBP antibody (ABIN542629)

Harauz, Ishiyama, Hill, Bates, Libich, Farès: "Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis." in: Micron (Oxford, England : 1993), Vol. 35, Issue 7, pp. 503-42, (2004) (PubMed).

Schwartz, Hauben: "T cell-based therapeutic vaccination for spinal cord injury." in: Progress in brain research, Vol. 137, pp. 401-6, (2002) (PubMed).

Hauben, Agranov, Gothilf, Nevo, Cohen, Smirnov, Steinman, Schwartz: "Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease." in: The Journal of clinical investigation, Vol. 108, Issue 4, pp. 591-9, (2001) (PubMed).

Target Details for MBP

Target: MBP (Myelin Basic Protein (MBP))

Alternative Name: Myelin Basic Protein (MBP Products)

Synonyms: C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, MGC115135 antibody, myelin basic protein antibody, myelin basic protein a antibody, myelin basic protein L homeolog antibody, MBP antibody, Mbp antibody, mbpa antibody, mbp antibody, mbp.L antibody