SMURF2 antibody (SMAD Specific E3 Ubiquitin Protein Ligase 2)

Details for Product anti-SMURF2 Antibody No. ABIN542769
Antigen
  • SMURF2
  • 2810411E22Rik
  • AI558114
  • AI649275
  • RGD1310067
  • wu:fb82a11
  • wu:fc41c02
  • SMAD specific E3 ubiquitin protein ligase 2
  • SMAD specific E3 ubiquitin protein ligase 2 S homeolog
  • SMURF2
  • smurf2
  • Smurf2
  • smurf2.S
Reactivity
Human
89
40
22
Host
Rabbit
82
6
1
Clonality
Polyclonal
Conjugate
This SMURF2 antibody is un-conjugated
8
6
6
4
4
4
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
57
40
37
19
13
13
8
2
1
1
Options
Plasmids, Primers & others Plasmids, Primers & others SMURF2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SMURF2 (SMURF2 Antibody Abstract)
Restrictions For Research Use only
Supplier Images
 image for anti-SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2) antibody (ABIN542769) Formalin-fixed and paraffin-embedded human cancer tissue reacted with SMURF2 polyclon...
Western Blotting (WB) image for anti-SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2) antibody (ABIN542769) The SMURF2 polyclonal antibody is used in Western blot to detect SMURF2 in mouse bra...
Product cited in: Zhang, Chang, Gehling, Hemmati-Brivanlou, Derynck: "Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 3, pp. 974-9, 2001 (PubMed).

Kavsak, Rasmussen, Causing, Bonni, Zhu, Thomsen, Wrana: "Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation." in: Molecular cell, Vol. 6, Issue 6, pp. 1365-75, 2001 (PubMed).

Lin, Liang, Feng: "Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling." in: The Journal of biological chemistry, Vol. 275, Issue 47, pp. 36818-22, 2001 (PubMed).

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