BCL2L11
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
HRP
Application Notes
Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Chen, Zhou: "Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 5, pp. 1235-40, (2004) (PubMed).
Sunters, Fernández de Mattos, Stahl, Brosens, Zoumpoulidou, Saunders, Coffer, Medema, Coombes, Lam: "FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines." in: The Journal of biological chemistry, Vol. 278, Issue 50, pp. 49795-805, (2003) (PubMed).
Luciano, Jacquel, Colosetti, Herrant, Cagnol, Pages, Auberger: "Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function." in: Oncogene, Vol. 22, Issue 43, pp. 6785-93, (2003) (PubMed).