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ErbB2/Her2 antibody (pTyr1248)

ErbB2/Her2 Reactivity: Human WB, DB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN542921
  • Target See all ErbB2/Her2 Antibodies
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Binding Specificity
    • 32
    • 29
    • 27
    • 26
    • 25
    • 23
    • 23
    • 21
    • 18
    • 16
    • 15
    • 13
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pTyr1248
    Reactivity
    • 510
    • 187
    • 164
    • 34
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 409
    • 148
    • 11
    • 5
    • 3
    • 3
    Rabbit
    Clonality
    • 412
    • 164
    • 2
    Polyclonal
    Conjugate
    • 267
    • 46
    • 37
    • 29
    • 25
    • 23
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 8
    • 8
    • 8
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This ErbB2/Her2 antibody is un-conjugated
    Application
    • 297
    • 229
    • 139
    • 98
    • 93
    • 92
    • 91
    • 80
    • 66
    • 50
    • 28
    • 20
    • 12
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit polyclonal antibody raised against synthetic phosphopeptide of ERBB2.
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Synthetic Peptide.
    Immunogen
    Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1248 of human ERBB2.
    Top Product
    Discover our top product ErbB2/Her2 Primary Antibody
  • Application Notes
    Western Blot (1:8000)
    Immunohistochemistry (1:50-1:100)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Beckers, Herrmann, Rieger, Drobyshev, Horsch, Hrabé de Angelis, Seliger: "Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis." in: International journal of cancer. Journal international du cancer, Vol. 114, Issue 4, pp. 590-7, (2005) (PubMed).

    Provinciali, Re, Donnini, Orlando, Bartozzi, Di Stasio, Smorlesi: "Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 1, pp. 36-45, (2005) (PubMed).

    Yee, Young, Rosol, Vanbuskirk, Clinton: "Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast cancer in mice independently of the PPARgamma ligand rosiglitazone." in: The Journal of nutrition, Vol. 135, Issue 5, pp. 983-8, (2005) (PubMed).

  • Target
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Alternative Name
    CD340 / ERBB2 / HER2 (ErbB2/Her2 Products)
    Synonyms
    CD340 antibody, HER-2 antibody, HER-2/neu antibody, HER2 antibody, MLN 19 antibody, NEU antibody, NGL antibody, TKR1 antibody, Erbb-2 antibody, Neu antibody, c-erbB2 antibody, c-neu antibody, mKIAA3023 antibody, wu:fv70f10 antibody, zgc:63601 antibody, erb2 antibody, erb-b2 receptor tyrosine kinase 2 antibody, ERBB2 antibody, Erbb2 antibody, erbb2 antibody
    Gene ID
    2064
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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