JAG2 antibody (C-Term)

Catalog No. ABIN542940

Product Details anti-JAG2 Antibody

Target: JAG2 (Jagged 2 (JAG2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of JAG2.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human JAG2.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-JAG2 antibody (ABIN542940)

Cama, Verginelli, Lotti, Napolitano, Morgano, DOrazio, Vacca, Perconti, Pepe, Romani, Vitullo, di Lella, Visone, Mannelli, Neumann, Raiconi, Paties, Moschetta, Tagliaferri, Veronese, Sanna et al.: "Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling. ..." in: Acta neuropathologica, Vol. 126, Issue 4, pp. 575-94, (2013) (PubMed).

Lindner, Booth, Prudovsky, Small, Maciag, Liaw: "Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction." in: The American journal of pathology, Vol. 159, Issue 3, pp. 875-83, (2001) (PubMed).

Hayashi, Kageyama, Ishizaka, Xia, Kihara, Oshima: "Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes." in: Journal of andrology, Vol. 22, Issue 6, pp. 999-1011, (2001) (PubMed).

Cereseto, Tsai: "Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division." in: Journal of cellular physiology, Vol. 185, Issue 3, pp. 425-31, (2000) (PubMed).

Target Details for JAG2

Target: JAG2 (Jagged 2 (JAG2))

Alternative Name: Jagged-2 / JAG2 (JAG2 Products)

Synonyms: D12Ggc2e antibody, Serh antibody, mJagged2-1 antibody, sm antibody, HJ2 antibody, SER2 antibody, jag2 antibody, serB antibody, zgc:152855 antibody, jagged 2 antibody, jagged 2b antibody, JAG2 antibody, jag2 antibody, Jag2 antibody, jag2b antibody

Gene ID: 3714

Pathways: Notch Signaling, Sensory Perception of Sound