Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) (MLL) antibody

Details for Product No. ABIN543317
Antigen
Reactivity
Human
57
17
11
Host
Rabbit
44
13
Clonality
Polyclonal
Conjugate
Un-conjugated
3
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
34
31
28
10
5
3
3
3
2
2
1
Options
Purpose Rabbit polyclonal antibody raised against synthetic peptide of MLL.
Immunogen A synthetic peptide (conjugated with KLH) corresponding to amino acids 312-343 at C-terminus of human MLL.
Antigen
Alternative Name MLL / HRX (MLL Antibody Abstract)
Application Notes Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.09 % sodium azide)
Storage 4 °C,-20 °C
Storage Comment Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Supplier Images
Image no. 1 for anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) (MLL) antibody (ABIN543317) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the MLL polyclo...
Product cited in: Pegram, Megonigal, Lange, Nowell, Rowley, Rappaport, Felix: "t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene." in: Blood, Vol. 96, Issue 13, pp. 4360-2, 2000 (PubMed).

Sano, Hayakawa, Piao, Kosaka, Nakamura: "Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11) (p21;q23)." in: Blood, Vol. 95, Issue 3, pp. 1066-8, 2000 (PubMed).

Megonigal, Cheung, Rappaport, Nowell, Wilson, Jones, Addya, Leonard, Kushner, Williams, Lange, Felix: "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 6, pp. 2814-9, 2000 (PubMed).