PADI4
Reactivity: Human
WB, FACS
Host: Mouse
Monoclonal
5B7
unconjugated
Application Notes
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Nakayama-Hamada, Suzuki, Kubota, Takazawa, Ohsaka, Kawaida, Ono, Kasuya, Furukawa, Yamada, Yamamoto: "Comparison of enzymatic properties between hPADI2 and hPADI4." in: Biochemical and biophysical research communications, Vol. 327, Issue 1, pp. 192-200, (2005) (PubMed).
Barton, Bowes, Eyre, Spreckley, Hinks, John, Worthington: "A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population." in: Arthritis and rheumatism, Vol. 50, Issue 4, pp. 1117-21, (2004) (PubMed).
Wang, Wysocka, Sayegh, Lee, Perlin, Leonelli, Sonbuchner, McDonald, Cook, Dou, Roeder, Clarke, Stallcup, Allis, Coonrod: "Human PAD4 regulates histone arginine methylation levels via demethylimination." in: Science (New York, N.Y.), Vol. 306, Issue 5694, pp. 279-83, (2004) (PubMed).
Target
PAD4 (PADI4)
(Peptidyl Arginine Deiminase, Type IV (PADI4))